oligomycin solubility

Found inside – Page 290TABLE I Melting Points and Specific Rotation Values for Purified Preparations of Oligomycins A , B , and C [ a ] 33 ... moderately soluble in ether , 95 per cent ethanol , and glacial acetic acid ( with the exception of oligomycin B , which is much ... Found inside – Page 1118... for carboxy groups of proteins [ 75 ] inhibits the activity of soluble mitochondrial ATPase with a high efficiency but has no influence on the ATPase activity of the SMPs of the factor F , of the octane / water boundary . The oligomycin - sensitive ... Found inside – Page 437437 Table 3 (Continued) Inhibitor Structure * | colo, Solubility Sodium amytal ... /NN ÖH NO2 Oligomycin C25H40–420, 408 10–6 M Slightly soluble Structural ... Found inside – Page 881Nitrophenols Oligomycin solubility of , 463 AE particles and , 386 , 390 as uncouplers , 470 ATPase assays and , 329-330 , 333 p - Nitrophenyl acetate , hydrolysis , rapid ATPase inhibitor and , 407 mixing device and , 246 ATP synthesis and ... Found insideExtent of inhibition of phosphorus was correlated with lipid solubility,217 ... the effect of oligomycin and a diphenolic compound diethylstilbestrol (DES) ... Found inside – Page 28January , 1955 Further Studies of the Preparation and Properties of Oligomycin WILLIAM JAMES HALLIDAY Under the ... A prominent attribute of oligomycin is its hydrophobic nature , as exemplified by the low solubility of the compound in ... Found inside – Page 1698Solubilities The oligomycins are stable compounds . Their inhibitory poSuggestions for Further Reading tency is little changed on storage at pH 3 to 10 at 37 ° C for 54 h ( 8 ) . They are almost insoluble in water but are soluble in C. Bränden ... Found inside – Page 2872... effects on aquatic ecostems have been undertaken using levels in excess of the water solubility of this pesticide . Our work ... Inhibition of oligomycin sensitive and insensitive fish adenosine triphosphatase activity by chlorinated hydrocarbon ... Found inside – Page 39... cytology / RABBITS , immunology / SOLUBILITY Organ - specific effects of ... chemically induced / OLIGOMYCIN , pharmacodynamics / SOLUBILITY / STAINS ... The book takes readings systematically through the target organs, before detailing current preventative and counter measures. Found inside – Page 269... ORGA NOPHCSEHORUS W73-02436 * OLIGOMYCIN , PHENYLS , POTASSIUM , SODIUM ... OXIDATION , SOLUBILITY , SOLID WASTES , SALT BALANCE , ORGAN W 74-06 747 IOR ... Found inside – Page 832Other Properties: The oligomycins are slightly soluble in water O (e.g., oligomycin A has a solubility of 2 μg per 100 mL at 25°C) and are considerable more ... Found inside – Page 437437 Table 3 ( Continued ) Inhibitor Structure Molecular weight Inhibitory concentration Solubility Sodium amytal 248 10-3M ... OH No , Oligomycin 408 10-6M C2H , 0-20 , Structural determination incomplete SMITH , PETERSON and McCoy ... Found inside – Page 87Ceratocystis ulmi , cerato - ulmin , characterization , solubility 420 . dimorphism , nutrition effects on 883 . dimorphism ... triphenyltin , oligomycin , association , Beta vulgaris infection 7210 drug resistance , oligomycin , triphenyltin 8897 isolates ... Found inside – Page 10C . Solubility Rough approximations of solubility have been accumulated in the course of the work . Oligomycin is soluble in a number of the common organic solvents . In methanol , ethanol , butanol , ethyl ether , glacial acetic acid , chloroform ... Found inside – Page 42The reason for this is the following : oligomycin is practically insoluble in Skelly , but the solubility increases very rapidly on adding small amounts of ethylacetate , acetone or oil . The Skelly precipitation was studied in detail in the recovery ... Found inside – Page 3076... was rinsed with ethanol between experiments to ensure removal of those compounds used which had low solubility in ... Oligomycin was purchased from the Wisconsin Alumni Research Foundation , and crystalline hexokinase 0.8 mm Na ... Found inside – Page 2120Another product , V # 4 containing 3 components , was analyzed to contain 68 per cent oligomycin A , 7.5 per cent oligomycin B , and 25 per cent oligomycin C. Macro ... The oligomycins have a very low solubility in an aqueous medium . Found inside – Page 39DNP and oligomycin in concentrations of more than 1 ug mg protein inhibit the ... The dependence of the solubility parameter of the hydrophobic label in the ... Found inside – Page 45William James Halliday. r. probably affect the physical nature (charge and solubility, for example) Found inside – Page 1927.3 7.4 Fo (fraction oligomycin) and can be inhibited by oligomycin and DCCD in both depleted and untreated SMPs. Clearly the soluble Fl-ATPase will not be ... Found inside – Page 1698The threedimensional structure of oligomycin B was determined by von Glehn et al . ( 7 ) . ... Their solubility in water including 1 % ethanol seems , from examination using [ H ] -labeled oligomycin made in our laboratory and not commercially ... Found inside – Page 106The oligomycin-sensitive complex has a higher molecular weight and has an ... Phospholipid content - + Water solubility + - Cold lability + - Membrane ... Found inside – Page 71Ethanol solutions of oligomycin were prepared at several different concentrations . Dilution of this solution with water showed the solubility limit to be about 10 MM ( final ethanol concentration = 1 % ) . Since oligomycin is not very soluble ( 100 ) ... Found inside – Page 164... Water solubility Yes No Cold lability Yes No Membrane formation No Yes Phospholipid requirement for activity No Yes Inhibition by oligomycin, DCCD, etc. Found inside – Page 585Oligomycin Complex , Rutamycin and Aurovertin Paul D. Shaw The work described in this chapter resulted largely from the ... The solubility properties of all three are similar in that they are generally soluble in organic solvents , except ... Found inside – Page 189... dyes measure the potential of the plasma membrane is probably due to the high solubility of safranine in aqueous solutions ... When also Fis present a slow reversal of the trace is obtained upon the addition of rotenone and oligomycin plus ... Found inside – Page 2787This procedure served to remove trapped soluble protein from vesicles and helped verify that dissociable V subunits visualized in ... All incubations were performed at 22 ° C . Oligomycin ( F - type ATPase inhibitor ) was obtained from Sigma . Found inside – Page 17The temperature was 37 ° C . Oligomycin A ( Sigma ) was added from stock solutions ( 1 to 20 mg oligomycin ... Oligomycin was not completely soluble at the concentration used in the A0 binding experiments ( 8.2 ug / ml ) . As a result the light ... Found inside – Page 142Oligomycin is inhibitory on the utilization of ATP at the site of active transport ( Robinson , 1971 ) . ... Higher concentrations of antimycin A and oligomycin could not be tested because the solubility limit of each was reached at 5 x 10-2 . With low ... Found inside – Page 153SDS gel electrophoretic analysis of oligomycin affinity labeled ATPase following degradation with proteases . The protein ... and solubility properties exhibited by the oligomycin affinity labeled protein products in these studies . The gel ... Found inside – Page 38The biological assay was used for those solvents in which oligomycin exhibits a very low solubility ; both weight and assay were done where possible . The results appear in table 3 . The water solubility of oligomycin is extremely low and ... Found inside – Page 3Souro and isolation of oligomycin , who succeeded in increasing yields substantially . By controlling pH and ... problem of the lack of information on the differences in inhibition , solubility , and other factors among the A , B , and C components . Found inside – Page 105Hemker , H . C . , “ Lipid solubility as a factor influencing the activity of uncoupling phenols , ” Biochim . Biophys . Acta , 63 ... A mitochondrial factor conferring oligomycin - sensitivity on soluble mitochondrial ATPase , ” Biochem . Biophys . Res . Found inside – Page 198This activity was not inhibited by oligomycin and was termed the FI-ATPase ('fraction 1'). Naturally, the soluble F1 was incapable of ATP synthesis. Found inside – Page 170TABLE VI PROPERTIES of F1 AND of THE OLIGOMYCIN-SENSITIVE ATPASE CoMPLEx ... Physical Phospholipid content - Water solubility + Cold lability + Number of ... Found inside – Page 474Water solubility is an indication that these proteins are not in contact ... 12); when bound back to the membrane, F1 becomes oligomycin sensitive (Fig. Found inside – Page 93The same reactions can also be obtained with a soluble oligomycin - sensitive ATPase , and the product of both resembles subunit 9 in its electrophoretic and solubility properties . Interactions during Mutagenesis Rationale . Found inside – Page 28Lancet 2 ( 8043 ) : 875 , 22 Oct 77 OLIGOMYCIN PHARMACODYNAMICS Nitrofurantoin solubility in aqueous pyridoxine hydrochloride solutions ( letter ] ... Found inside – Page 195... a protein of low solubility to which coupling factors are strongly absorbed ... Oligomycin sensitivity corgferring protein (OSCP) Tzagolofl'et al. Found inside – Page 26Marty ( 1957 ) has shown oligomycin to possess a low solubility in water , a necessary property for a nonsystemic protectant , since it will be subject to washing of rain and other weathering . It was therefore decided to further study oligomycin ... Found inside – Page 3The antibiotic oligomycin was obtained by Smith in 1953 ( 1,2 ) from a strain of streptomyces very similar to ... However , the use of oligomycin in the treatment of human diseases was precluded by its parenteral toxicity and low water solubility . Found inside – Page 72This is no mean task, however, because the solubility of hydrogen in aqueous media is ... 2,4-dinitrophenol or pentachlorophenol, but not by oligomycin. Found inside – Page 302Because of its hydrophobic residues and solubility in organic solvents, ... Oligomycin or DCCD plugs this leak and restores the ability to maintain a H* ... Found inside – Page 133[ 1 ] Oligomycin was the most effective of 8 antibiotics tested against Tilletia caries ( wheat smut fungus ) ... SOLUBILITY s . most organic solvents ; sl . Found inside – Page 954OSCP (oligomycin sensitivity-conferring protein), 89 Osmolytes accumulation, intracellular swelling from, 456s, 457 amino ... See also Diffusion driving force, 314 mediated, 314, 317 solubility-diffusion process for, 317 transepithelial, 313–314 ... Found inside – Page 334... 256-259 catalytic expressions of soluble P), 239-251 catalytic sites, ... 241 Oligomycin-sensitivity-conferring protein, 226 Oligonucleotide binding, ... Found inside – Page 585Oligomycin Complex, Rutamycin and Aurovertin Paul D. Shaw The work described in this ... The solubility properties of all three are similar in that they are ... 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